A-11

A11 (ANXA1-derived 11 amino acid-long peptide) is a ANXA1-EphA2 interaction-blocking peptide. A11 reduces ANXA1 bound to EphA2 and increases Cbl (the E3 ubiquitin ligase of EphA2) bound to EphA2. A11 inhibits the proliferation, migration and invasion of nasopharyngeal carcinoma cells. A11 inhibits angiogenesis. A11 can be used in studies related to nasopharyngeal carcinoma.


Cat. No.: EX-A13009	Purity: >98%

	Chemical structure of A-11

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
500mg	1080	In-stock

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CAS No.	2412926-30-6
Purity	>98%
Formula	C117H204N46O32
Mol Weight	2767.1606
Color	White to off-white
State	Solid
Solubility	DMSO : 33.33 mg/mL H2O : 22.2 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -80°C, 2 years , -20°C, 1 year; sealed storage, away from moisture. In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Feng J, et al. ANXA1 Binds and Stabilizes EphA2 to Promote Nasopharyngeal Carcinoma Growth and Metastasis. Cancer Res. 2020;80(20):4386-4398.
CoA	CoA of A-11

Smiles:	[C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC2=CC=C(O)C=C2)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N


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