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Product Information:

Z-FA-FMK

Z-FA-FMK is a potent Cathepsin B and L inhibitor. Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.

Cat. No.: EX-A2188    Purity: >98%
Z-FA-FMK
For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg550In-stock
500mg750In-stock
1g1050In-stock
2g1780In-stock
3g2400In-stock
5g3550In-stock


Synonyms(1S)-Z-FA-FMK
CAS No.197855-65-5
Purity>98%
FormulaC21H23FN2O4
Mol Weight386.4167
Appearancewhite to off-white solid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃, sealed storage, away from moisture; 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Lopez-Hernandez FJ, et, al. Z-FA-fmk inhibits effector caspases but not initiator caspases 8 and 10, and demonstrates that novel anticancer retinoid-related molecules induce apoptosis via the intrinsic pathway. Mol Cancer Ther. 2003 Mar;2(3):255-63.

[2]. Kim M, et, al. Z-FA-FMK as a novel potent inhibitor of reovirus pathogenesis and oncolysis in vivo. Antivir Ther. 2010;15(6):897-905.

[3]. Gezginci-Oktayoglu S, et, al. Effects of Z-FA.FMK on D-galactosamine/tumor necrosis factor-alpha-induced kidney injury and oxidative stress in mice : effects of Z-FA.FMK on TNF-alpha-mediated kidney injury. Mol Cell Biochem. 2008 Feb;309(1-2):9-20.

CoACoA of Z-FA-FMK
Smiles:CC(NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)OCC1=CC=CC=C1)C(=O)CF

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