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Product Information:

Tubulysin B

Tubulysin B is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.

Cat. No.: EX-A5466    Purity: >98%
Chemical
Chemical structure of Tubulysin B


For research only, Do not use for Human!

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CAS No.205304-87-6
Purity>98%
FormulaC42H63N5O10S
Mol Weight830.042
Appearancesolid powder
Shelf Life>2 years if stored properly
StoragePowder -20℃ 1 year; Powder -80℃ 2 year; In solvent -20℃ 1 month;
 
 
Reference:  

[1]. Leamon, Christopher P et al. “Prostate-Specific Membrane Antigen-Specific Antitumor Activity of a Self-Immolative Tubulysin Conjugate.” Bioconjugate chemistry vol. 30,6 (2019): 1805-1813.

[1]. Vlahov, Iontcho R et al. “Acid mediated formation of an N-acyliminium ion from tubulysins: a new methodology for the synthesis of natural tubulysins and their analogs.” Bioorganic & medicinal chemistry letters vol. 21,22 (2011): 6778-81.

CoACoA of Tubulysin B

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