TMX-4116

TMX-4116 is a casein kinase 1α (CK1α) degrader. TMX-4116 shows the degradation preference for CK1α with DC50s less than 200 nM in MOLT4, Jurkat, and MM.1S cells. TMX-4116 can be used for the research of multiple myeloma.


Cat. No.: EX-A6316	Purity: >98%

	Chemical structure of TMX-4116

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
100mg	5885	Inquire

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Purity	>98%
Formula	C17H19N5O4S
Mol Weight	389.429
Appearance	solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Teng M, et al. Development of PDE6D and CK1α Degraders through Chemical Derivatization of FPFT-2216. J Med Chem. 2022 Jan 13;65(1):747-756.
CoA	CoA of TMX-4116


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