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Product Information:

Somapacitan

Somapacitan is a novel long-acting, reversible albumin-binding growth hormone (GH) derivative for treatment of growth hormone deficiency.

Cat. No.: EX-A4353    Purity: >98%
Chemical
Chemical structure of Somapacitan


For research only, Do not use for Human!

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CAS No.1338578-34-9
Purity>98%
FormulaC54H95N13O20S2
Mol Weight1310.537
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Thygesen, Peter et al. “Nonclinical pharmacokinetic and pharmacodynamic characterisation of somapacitan: A reversible non-covalent albumin-binding growth hormone.” Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society vol. 35 (2017): 8-16.

[2]. Petersen, Maj et al. “Tissue Distribution and Receptor Activation by Somapacitan, a Long Acting Growth Hormone Derivative.” International journal of molecular sciences vol. 21,4 1181. 11 Feb. 2020

[3]. Battelino, Tadej et al. “Somapacitan, a once-weekly reversible albumin-binding GH derivative, in children with GH deficiency: A randomized dose-escalation trial.” Clinical endocrinology vol. 87,4 (2017): 350-358.

CoACoA of Somapacitan
Smiles:C(CCCCCCCC1=NNN=N1)CCCCCCCC(=O)NS(=O)(=O)CCCC(=O)NCCOCCOCC(=O)N[C@@H](CCC(=O)N[C@@H](CCC(=O)NCCOCCOCC(=O)N[C@@H](CCCCNC(=O)CSC[C@@H](C(=O)O)N)C(=O)N)C(=O)O)C(=O)O

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