Salcaprozate sodium

Salcaprozate sodium (SNAC), an oral absorption promoter, and has the potential as a delivery agent for oral forms of heparin and insulin. Salcaprozate sodium could increase passive transcellular permeation across small intestinal epithelia based on increased lipophilicity arising from non-covalent macromolecule complexation.


Cat. No.: EX-A3434	Purity: 99.98% HPLC; Assay:99.84%

	Chemical structure of Salcaprozate sodium

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10g	550	In-stock
25g	750	In-stock
50g	950	In-stock
100g	1500	In-stock

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Synonyms	SNAC
CAS No.	203787-91-1
Purity	99.98% HPLC; Assay:99.84%
Formula	C15H20NNaO4
Mol Weight	301.3134
Appearance	white solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 1 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Riley MGI, et, al. Subchronic oral toxicity of salcaprozate sodium (SNAC) in Sprague-Dawley and Wistar rats. Int J Toxicol. Jul-Aug 2009; 28(4):278-93. [2]. Twarog C, et, al. Intestinal Permeation Enhancers for Oral Delivery of Macromolecules: A Comparison between Salcaprozate Sodium (SNAC) and Sodium Caprate (C 10). Pharmaceutics. 2019 Feb 13; 11(2):78. [3]. Li Y, et, al. Impact of Sodium N-[8-(2-Hydroxybenzoyl)amino]-caprylate on Intestinal Permeability for Notoginsenoside R1 and Salvianolic Acids in Caco-2 Cells Transport and Rat Pharmacokinetics. Molecules. 2018 Nov 16; 23(11):2990.
CoA	CoA of Salcaprozate sodium

Smiles:	C1=CC=C(C(=C1)C(=O)NCCCCCCCC(=O)[O-])O.[Na+]


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