Raseglurant

Raseglurant (ADX-10059) is a mGlu5 receptor negative allosteric modulator. Raseglurant is effective against migraine. Raseglurant reduces the Haloperidol-induced catalepsy in mice.


Cat. No.: EX-A11409	Purity: >98%

	Chemical structure of Raseglurant

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	535	In-stock
500mg	848	In-stock
1g	1336	In-stock
5g	get quote

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Synonyms	ADX-10059
CAS No.	757950-09-7
Purity	>98%
Formula	C15H13FN2
Mol Weight	240.2755
Appearance	Off-white to yellow solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃, protect from light, 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Romero-Fernandez W, et al. The mGlu5 Receptor Protomer-Mediated Dopamine D2 Receptor Trans-Inhibition Is Dependent on the Adenosine A2A Receptor Protomer: Implications for Parkinson's Disease. Mol Neurobiol. 2022 Oct;59(10):5955-5969. [2]. Font J, et al. Correction: Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator. Elife. 2018 Jan 8;7:e34752.
CoA	CoA of Raseglurant

Smiles:	NC1=C(C)C=C(C)N=C1C#CC2=CC=CC(F)=C2


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