RK-33

RK-33 is a first-in-class small molecule inhibitor of DDX3 (a RNA helicase) and causes G1 cell cycle arrest, induces apoptosis, and promotes radiation sensitization in DDX3-overexpressing cells.


Cat. No.: EX-A4211	Purity: >98%

	Chemical structure of RK-33

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	685	In-stock
1g	1050	In-stock
5g	3860	In-stock
10g	get quote	In-stock
25g	get quote	Inquire

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Synonyms	RK33
CAS No.	1070773-09-9
Purity	>98%
Formula	C23H20N6O3
Mol Weight	428.4433
Appearance	Light yellow to yellow solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Xie M,et al. RK-33 radiosensitizes prostate cancer cells by blocking the RNA helicase DDX3. Cancer Res. 2016 Sep 12. [2]. Bol GM, e tal. PLGA nanoparticle formulation of RK-33: an RNA helicase inhibitor against DDX3. Cancer Chemother Pharmacol. 2015 Oct;76(4):821-7.
CoA	CoA of RK-33

Smiles:	O=C1N(CC2=CC=C(OC)C=C2)C3=NC=NC4=C(N=CN4CC5=CC=C(OC)C=C5)C3=N1


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