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Product Information:
| Cat. No.: EX-A5434 | Purity: >98% |
 | |
| Chemical structure of Proxalutamide |
| Size | Unit Price (US$) | Stock | Quantity | Order |
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| Send PO to E-mail:order@excenen.com; or Fax:+86 020 81619670 |
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| Synonyms | GT0918 |
|---|---|
| CAS No. | 1398046-21-3 |
| Purity | >98% |
| Formula | C24H19F4N5O2S |
| Mol Weight | 517.499 |
| Appearance | solid powder |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
| Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Reference: | [1]. Yang M, et al. Microenvironmental pH-modified solid dispersions to enhance the dissolution and bioavailability of poorly water-soluble weakly basic GT0918, a developing anti-prostate cancer drug: preparation, characterization and evaluation in vivo. Int J Pharm. 2014 Nov 20;475(1-2):97-109.
[2]. Feng Qu, et al. Metabolomic profiling to evaluate the efficacy of proxalutamide, a novel androgen receptor antagonist, in prostate cancer cells. Invest New Drugs. 2020 Oct;38(5):1292-1302. [3]. Monitoring Editor, et al. Proxalutamide Significantly Accelerates Viral Clearance and Reduces Time to Clinical Remission in Patients with Mild to Moderate COVID-19: Results from a Randomized, Double-Blinded, Placebo-Controlled Trial. Cureus. 2021 Feb; 13(2): e13492. [4]. Hua Sang, et al. Quantitative determination of proxalutamide in rat plasma and tissues using liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom. 2021 Feb 15;35(3):e9003. |
| CoA | CoA of Proxalutamide |
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