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Product Information:

Pan-RAS-IN-2

Pan-rasin-2 (compound 6A) is a molecular glues that targets RAS. Pan-rasin-2 has significant inhibitory activity on cell proliferation of RAS mutant cell lines. Pan-rasin-2 can form ternary complexes with cyclophilin A (CYPA) and RAS (ON) proteins and the formation of ternary complexes can block the binding of RAF downstream of RAS, which has anti-tumor effects.

Cat. No.: EX-A9620    Purity: >98%
Chemical
Chemical structure of Pan-RAS-IN-2


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg2800In-stock
250mg3900In-stock
500mg4900In-stock
1gget quoteIn-stock


CAS No.3034673-92-9
Purity>98%
FormulaC46H60N8O5S
Mol Weight837.084
Appearancewhite to light yellow solid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃, 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Y Zhang, et al. Macrocyclic derivative and use thereof. WO2024067857A1. 2023-09-28

CoACoA of Pan-RAS-IN-2

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