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Product Information:

OPB-171775

OPB-171775 is a novel anticancer agent and demonstrated its potent efficacy against GISTs. OPB-171775 acts as a molecular glue between PDE3A and SLFN12 and exerts anticancer activity through the RNase activity of SLFN12.

Cat. No.: EX-A9729    Purity: HPLC >98%, ee>98%
Chemical
Chemical structure of OPB-171775


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg885In-stock
250mg1585In-stock
500mg2485In-stock
1g3585In-stock
2gget quoteIn-stock
5gget quoteIn-stock


CAS No.2131210-15-4
PurityHPLC >98%, ee>98%
FormulaC15H18F2N2O3
Mol Weight312.3118
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Takaki, Emiri O et al. “A PDE3A-SLFN12 Molecular Glue Exhibits Significant Antitumor Activity in TKI-Resistant Gastrointestinal Stromal Tumors.” Clinical cancer research : an official journal of the American Association for Cancer Research vol. 30,16 (2024): 3603-3621. doi:10.1158/1078-0432.CCR-24-0096

CoACoA of OPB-171775

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