NDI-091143
NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay), a Ki of 7.0 nM and a Kd of 2.2 nM.
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Cat. No.: EX-A3332 | Purity: >98% |
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| Chemical structure of NDI-091143 |
For research only, Do not use for Human!
CAS No. | 2375840-87-0 |
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Purity | >98% |
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Formula | C20H14ClF2NO5S |
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Mol Weight | 453.844 |
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Appearance | solid powder |
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Solubility | Soluble in DMSO |
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Shelf Life | >2 years if stored properly |
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Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
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Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
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Reference: | [1]. Wei J, et al. Nature. 2019 Apr;568(7753):566-570. |
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CoA | CoA of NDI-091143 |
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Smiles: | O=C(OC)C1=CC(S(=O)(NC2=CC(C3=CC=CC=C3)=C(F)C=C2F)=O)=C(O)C(Cl)=C1 |
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