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Product Information:

MT-4129

Lorundrostat (MT-4129) is an orally active aldosterone synthase inhibitor. Lorundrostat can be used in studies of high blood pressure.

Cat. No.: EX-A8591    Purity: >98%
Chemical
Chemical structure of MT-4129


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg422In-stock
250mg800In-stock
500mg1280In-stock
1g2048In-stock
2g2998In-stock
5gget quoteIn-stock


SynonymsLorundrostat
CAS No.1820940-17-7
Purity>98%
FormulaC24H33N7O2
Mol Weight451.5645
AppearanceLight yellow to yellow solid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. International Nonproprietary Names for Pharmaceutical Substances (INN). WHO Drug Information, Vol. 36, No. 2, 2022.

[2]. Laffin LJ, et al. Aldosterone Synthase Inhibition With Lorundrostat for Uncontrolled Hypertension: The Target-HTN Randomized Clinical Trial. JAMA. 2023 Sep 26;330(12):1140-1150

[3]. Hideki K, et al., Novel disubstituted 1,2,4-triazine compounds. WO2015163427.

CoACoA of MT-4129
Smiles:CC(N[C@@H](CC1)CC[C@H]1NC(CN2CCN(CC2)C3=NN=CC(C4=CC=C(C=C4)C)=N3)=O)=O

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