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Product Information:

MOTS-c

MOTS-c Acetate is a mitochondrial-derived peptide. MOTS-c acetate induces the accumulation of AMP analog AICAR, increases activation of AMPK and expression of its downstream GLUT4. MOTS-c acetate induces glucose uptake and improves insulin sensitivity.

Cat. No.: EX-A6267    Purity: >98%
Chemical
Chemical structure of MOTS-c


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg385In-stock
50mg585In-stock
100mg985In-stock
1g2685In-stock


SynonymsMOTS-c acetate
CAS No.1627580-64-6
Purity>98%
FormulaC101H152N28O22S2
Mol Weight2174.592
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -80℃ 2 years; -20℃ 1 year; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Lee, Changhan et al. “The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance.” Cell metabolism vol. 21,3 (2015): 443-54. doi:10.1016/j.cmet.2015.02.009

[2]. Kong, Byung Soo et al. “Mitochondrial-encoded MOTS-c prevents pancreatic islet destruction in autoimmune diabetes.” Cell reports vol. 36,4 (2021): 109447. doi:10.1016/j.celrep.2021.109447

[3]. Mohtashami, Zahra et al. “MOTS-c, the Most Recent Mitochondrial Derived Peptide in Human Aging and Age-Related Diseases.” International journal of molecular sciences vol. 23,19 11991. 9 Oct. 2022, doi:10.3390/ijms231911991

[4]. Kumagai, Hiroshi et al. “MOTS-c reduces myostatin and muscle atrophy signaling.” American journal of physiology. Endocrinology and metabolism vol. 320,4 (2021): E680-E690. doi:10.1152/ajpendo.00275.2020

CoACoA of MOTS-c

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