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Product Information:

MLT-231

MLT-827 is an MALT1 allosteric inhibitor. MLT-231 potently and selectively inhibits the proteolytic activity of MALT1 in NF-κB-dependent assays.

Cat. No.: EX-A12021    Purity: >98%
Chemical
Chemical structure of MLT-231


For research only, Do not use for Human!

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CAS No.2682102-10-7
Purity>98%
FormulaC19H19ClF3N7O2
Mol Weight469.848
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Pissot Soldermann, Carole et al. “Discovery of Potent, Highly Selective, and In Vivo Efficacious, Allosteric MALT1 Inhibitors by Iterative Scaffold Morphing.” Journal of medicinal chemistry vol. 63,23 (2020): 14576-14593. doi:10.1021/acs.jmedchem.0c01245

CoACoA of MLT-231
Smiles:N(C(NC=1C=C(C(F)(F)F)N=CC1)=O)C2=C(N3C(N=C2)=CC(Cl)=N3)N4[C@@H](C)COC[C@@H]4C

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