ML266

ML266 is glucocerebrosidase (GCase) molecule chaperone with IC50 of 2.5 µM. ML266 binds to GCase and transports of the mutant protein to the lysosome, and resume the activity of GCase. ML266 dose not inhibit the GCase enzyme’s action. ML266 has the potential for the research of gaucher disease .


Cat. No.: EX-A2607	Purity: >98%

	Chemical structure of ML266

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	992	In-stock
1g	1786	In-stock
5g	Get quote	In-stock

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CAS No.	1462267-08-8
Purity	>98%
Formula	C24H22BrN3O4
Mol Weight	496.353
Appearance	white to off-white solid powder
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Rogers S, et al. Discovery, SAR, and Biological Evaluation of Non-inhibitory Chaperones of Glucocerebrosidase. 2012 Mar 27 [updated 2013 Mar 7].
CoA	CoA of ML266

Smiles:	CN(C(=O)CNC(=O)C1=CC=CC=C1OCC(=O)NC1=CC=C(Br)C=C1)C1=CC=CC=C1


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