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Product Information:

MGL-3196

Resmetirom (MGL-3196) is a highly selective thyroid hormone receptor β (THR-β) agonist with an EC50 value of 0.21 μM.

Cat. No.: EX-A2477    Purity: >99%
Chemical
Chemical structure of MGL-3196


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg425In-stock
500mg625In-stock
1g885In-stock
5g2475In-stock
10g3712In-stock
25g6310In-stock


SynonymsResmetirom
CAS No.920509-32-6
Purity>99%
FormulaC17H12Cl2N6O4
Mol Weight435.221
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Kelly MJ, et al. Discovery of 2-[3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β agonist in clinical trials for the treatment of dyslipidemia. J Med Chem. 2014 May 22;57(10):3912-23.

CoACoA of MGL-3196
Smiles:CC(C)C1=CC(OC2=C(Cl)C=C(C=C2Cl)N2N=C(C#N)C(=O)NC2=O)=NNC1=O

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