MGL-3196
Resmetirom (MGL-3196) is a highly selective thyroid hormone receptor β (THR-β) agonist with an EC50 value of 0.21 μM.
|
|
|
| Cat. No.: EX-A2477 | Purity: >99% |
|  |
| Chemical structure of MGL-3196 |
For research only, Do not use for Human!
| Synonyms | Resmetirom |
|---|
| CAS No. | 920509-32-6 |
|---|
| Purity | >99% |
|---|
| Formula | C17H12Cl2N6O4 |
|---|
| Mol Weight | 435.221 |
|---|
| Appearance | solid powder |
|---|
| Solubility | Soluble in DMSO |
|---|
| Shelf Life | >2 years if stored properly |
|---|
| Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
|---|
| Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
|---|
| |
|---|
| | |
|---|
| Reference: | [1]. Kelly MJ, et al. Discovery of 2-[3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β agonist in clinical trials for the treatment of dyslipidemia. J Med Chem. 2014 May 22;57(10):3912-23.
|
|---|
| CoA | CoA of MGL-3196 |
|---|
| Smiles: | CC(C)C1=CC(OC2=C(Cl)C=C(C=C2Cl)N2N=C(C#N)C(=O)NC2=O)=NNC1=O |
|---|
KEYWORDS: buy MGL-3196 | MGL-3196 supplier | purchase | cost | manufacturer | order | distributor | buy 920509-32-6 | 920509-32-6 supplier
Inhibitor Specialist 