MCC950 sodium

MCC950 sodium (CP-456773 sodium; CRID3 sodium salt) is a potent, selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively.


Cat. No.: EX-A2838	Purity: >99%

	Chemical structure of MCC950 sodium

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	250	In-stock
500mg	400	In-stock
1g	700	In-stock
2g	1100	In-stock
5g	2400	In-stock
10g	3600	In-stock

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Synonyms	CP-456773 sodium
Synonyms 2	CRID3 sodium
CAS No.	256373-96-3
Purity	>99%
Formula	C20H23N2NaO5S
Mol Weight	426.462
Appearance	Off-white to yellow
Solubility	Soluble in DMSO/water
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, sealed storage, away from moisture; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Coll RC, et al. A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nat Med. 2015 Mar;21(3):248-55. [2]. Zhai Y, et al. Inhibiting the NLRP3 Inflammasome Activation with MCC950 Ameliorates Diabetic Encephalopathy in db/db Mice. Molecules. 2018 Feb 27;23(3). pii: E522.
CoA	CoA of MCC950 sodium

Smiles:	[Na+].CC(C)(O)C1=COC(=C1)S(=O)(=O)[N-]C(=O)NC1=C2CCCC2=CC2=C1CCC2


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