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Product Information:

Linaclotide

Linaclotide developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation, and is a potent and selective guanylate cyclase C agonist.

Cat. No.: EX-A6257    Purity: >98%
Chemical
Chemical structure of Linaclotide


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg885In-stock
1g1550In-stock
2g2750In-stock
5gget quoteIn-stock


CAS No.851199-59-2
Purity>98%
FormulaC59H79N15O21S6
Mol Weight1526.736
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Bryant, Alexander P et al. “Linaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tract.” Life sciences vol. 86,19-20 (2010): 760-5. doi:10.1016/j.lfs.2010.03.015

[2]. Love, Bryan L et al. “Linaclotide: a novel agent for chronic constipation and irritable bowel syndrome.” American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists vol. 71,13 (2014): 1081-91. doi:10.2146/ajhp130575

CoACoA of Linaclotide

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