LY3437943

Retatrutide (LY3437943) is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively.


Cat. No.: EX-A7826E	Purity: >98%

	Chemical structure of LY3437943

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	400	In-stock
100mg	800	In-stock
250mg	1400	In-stock
500mg	1900	In-stock
1g	2900	In-stock
2g	4640	In-stock

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Synonyms	Retatrutide
CAS No.	2381089-83-2
Purity	>98%
Formula	C221H342N46O68
Mol Weight	4731.3477
Appearance	White solid powder
Solubility	Soluble in water
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Urva, Shweta et al. “LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial.” Lancet (London, England) vol. 400,10366 (2022): 1869-1881. [2]. Tamer Coskun, et al. LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept. Cell Metab. 2022 Sep 6;34(9):1234-1247.e9.
Data Sheet	Data sheet of LY3437943
CoA	CoA of LY3437943
SDS	SDS of LY3437943


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