Product Information:
Cat. No.: EX-A1981 | Purity: 98.72% |
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Synonyms | LOXO-101 |
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Synonyms 2 | Larotrectinib |
CAS No. | 1223403-58-4 |
Purity | 98.72% |
Formula | C21H22F2N6O2 |
Mol Weight | 428.4352 |
Appearance | solid powder |
Solubility | Soluble in DMSO |
Shelf Life | >2 years if stored properly |
Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Reference: | [1]. Ghilardi JR, et al. Administration of a tropomyosin receptor kinase inhibitor attenuates sarcoma-induced nerve sprouting, neuroma formation and bone cancer pain. Mol Pain. 2010, 6:87.
[2]. Vaishnavi A, et al. Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer. Nat Med. 2013, 19(11):1469-72. |
CoA | CoA of LOXO101 |
Smiles: | O[C@H]1CCN(C1)C(=O)NC1=C2N=C(C=CN2N=C1)N1CCC[C@@H]1C1=CC(F)=CC=C1F |
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