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Product Information:

LOE 908 hydrochloride

LOE 908 hydrochloride is a non-selective cation channel (NSCC) inhibitor[1].

Cat. No.: EX-A15250    Purity: >98%
Chemical
Chemical structure of LOE 908 hydrochloride


For research only, Do not use for Human!

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CAS No.143482-60-4
Purity>98%
FormulaC41H49ClN2O9
Mol Weight749.289
 
 
Reference:  

[1]. Krautwurst D, et al. The isoquinoline derivative LOE 908 selectively blocks vasopressin-activated nonselective cation currents in A7r5 aortic smooth muscle cells. Naunyn Schmiedebergs Arch Pharmacol. 1994 Mar;349(3):301-7.

[2]. Cheney JA, et al. The novel compound LOE 908 attenuates acute neuromotor dysfunction but not cognitive impairment or cortical tissue loss following traumatic brain injury in rats. J Neurotrauma. 2000 Jan;17(1):83-91.

CoACoA of LOE 908 hydrochloride
Smiles:COC1=C(C(=C(C=C1)CCN(CCC2=C(C(=C(C=C2)OC)OC)OC)C(=O)C(C3=CC=CC=C3)C4=NCCC5=CC(=C(C=C54)OC)OC)OC)OC.Cl

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