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Product Information:

KO-539

Ziftomenib (KO-539) is a potent and selective menin inhibitor.

Cat. No.: EX-A5611    Purity: >98%
Chemical
Chemical structure of KO-539


For research only, Do not use for Human!

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1g1200In-stock
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SynonymsZiftomenib
CAS No.2134675-36-6
Purity>98%
FormulaC33H42F3N9O2S2
Mol Weight717.871
AppearanceLight brown to brown Solid powder
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Rausch, Johanna et al. “Menin inhibitor ziftomenib (KO-539) synergizes with drugs targeting chromatin regulation or apoptosis and sensitizes acute myeloid leukemia with MLL rearrangement or NPM1 mutation to venetoclax.” Haematologica vol. 108,10 2837-2843. 1 Oct. 2023, doi:10.3324/haematol.2022.282160

[2]. Tao Wu, et al. Substituted inhibitors of menin-mll and methods of use. WO2017161028A1.

CoACoA of KO-539

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