KIF18A-IN-3

KIF18A-IN-3 is a potent KIF18A inhibitor (IC50=61 nM). KIF18A-IN-3 causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues. KIF18A-IN-3 can be used for researching cancer[1].


Cat. No.: EX-A14865	Purity: >98%

	Chemical structure of KIF18A-IN-3

For research only, Do not use for Human!

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CAS No.	2600577-49-7
Purity	>98%
Formula	C28H38N4O5S2
Mol Weight	574.755

Reference:	[1]. Tamayo NA, et al. Targeting the Mitotic Kinesin KIF18A in Chromosomally Unstable Cancers: Hit Optimization Toward an In Vivo Chemical Probe. J Med Chem. 2022;65(6):4972-4990.
CoA	CoA of KIF18A-IN-3

Smiles:	CC1(CC1)S(=O)(=O)NC2=CC(=C(C=C2)C(=O)NC3=CC(=CC=C3)S(=O)(=O)NC(C)(C)C)N4CCC5(CC5)CC4


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