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Product Information:

IDOR-1117-2520

IDOR-1117-2520 is a potent and selective antagonist of CCR6. IDOR-1117-2520 antagonizes the CCL20-mediated calcium flow (IC50 = 63 nM) and inhibits β-arrestin recruitment to human CCR6 (IC50 = 30 nM) in cells expressing recombinant human CCR6. IDOR-1117-2520 can be used for research of autoimmune diseases.

Cat. No.: EX-A9084    Purity: >98%
Chemical
Chemical structure of IDOR-1117-2520


For research only, Do not use for Human!

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CAS No.2737274-49-4
Purity>98%
FormulaC25H32N4O3
Mol Weight436.5466
Appearancewhite to off-white powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder 4℃, 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Meyer EA, et al. Discovery of the Clinical Candidate IDOR-1117-2520: A Potent and Selective Antagonist of CCR6 for Autoimmune Diseases. J Med Chem. 2024 May 10.

CoACoA of IDOR-1117-2520

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