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Product Information:

GCN2iB

GCN2iB is an ATP-competitive inhibitor of a serine/threonine-protein kinase general control nonderepressible 2 (GCN2), with an IC50 of 2.4 nM.

Cat. No.: EX-A4931    Purity: >98%
Chemical
Chemical structure of GCN2iB


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg985In-stock
250mg1685In-stock
500mg2585In-stock
1g3785In-stock
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CAS No.2183470-12-2
Purity>98%
FormulaC18H12ClF2N5O3S
Mol Weight451.834
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Nakamura A, et al. Inhibition of GCN2 sensitizes ASNS-low cancer cells by disrupting the amino acid response. Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7776-E7785.
CoACoA of GCN2iB
Smiles:COC1=C(C=C(C=N1)Cl)S(=O)(=O)NC2=C(C(=C(C=C2)F)C#CC3=CN=C(N=C3)N)F

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