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Product Information:

FT-671

FT671 is a potent, non-covalent and selective USP7 inhibitor with an IC50 of 52 nM and binds to the USP7 catalytic domain with a Kd of 65 nM.

Cat. No.: EX-A4777    Purity: 98+%
Chemical
Chemical structure of FT-671


For research only, Do not use for Human!

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CAS No.1959551-26-8
Purity98+%
FormulaC24H23F4N7O3
Mol Weight533.4781
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Turnbull AP, et al. Molecular basis of USP7 inhibition by selective small-molecule inhibitors. Nature. 2017 Oct 26;550(7677):481-486.
CoACoA of FT-671
Smiles:FC1=CC=C(N2N=CC3=C2N=CN(CC4(O)CCN(C(C[C@@H](C(F)F)N5N=C(F)C=C5)=O)CC4)C3=O)C=C1

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