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Product Information:

DOSPA hydrochloride

DOSPA is a cationic lipid for RNA and vaccine delivery.

Cat. No.: EX-A5801    Purity: >95% HNMR
Chemical
Chemical structure of DOSPA hydrochloride


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg850In-stock
50mg1350In-stock
100mg1900In-stock
250mgget quoteIn-stock
500mgget quoteIn-stock
1gget quoteIn-stock


SynonymsDOSPA tetrahydrochloride
Synonyms 2DOSPA (S-isomer Chloride 4HCl) 
CAS No.913194-16-8
Purity>95% HNMR
FormulaC54H115Cl5N6O3
Mol Weight1073.794
AppearanceOff-white solid
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Hirsch-Lerner D, Zhang M, Eliyahu H, Ferrari ME, Wheeler CJ, Barenholz Y. Effect of "helper lipid" on lipoplex electrostatics. Biochim Biophys Acta. 2005 Aug 15;1714(2):71-84. doi: 10.1016/j.bbamem.2005.04.008. PMID: 16051183.

[2]. Moon IJ, Kang H, Seu YB, Chang BC, Song DK, Park JG. Marked transfection enhancement by the DPL (DNA/peptide/lipid) complex. Int J Mol Med. 2007 Oct;20(4):429-37. PMID: 17786272.

[3]. Simberg D, Danino D, Talmon Y, Minsky A, Ferrari ME, Wheeler CJ, Barenholz Y. Phase behavior, DNA ordering, and size instability of cationic lipoplexes. Relevance to optimal transfection activity. J Biol Chem. 2001 Dec 14;276(50):47453-9. doi: 10.1074/jbc.M105588200. Epub 2001 Sep 19. PMID: 11564736.

[4]. Boulanger C, Di Giorgio C, Gaucheron J, Vierling P. Transfection with fluorinated lipoplexes based on new fluorinated cationic lipids and in the presence of a bile salt surfactant. Bioconjug Chem. 2004 Jul-Aug;15(4):901-8. doi: 10.1021/bc049942+. PMID: 15264880.
Data SheetData sheet of DOSPA hydrochloride
CoACoA of DOSPA hydrochloride
SDSSDS of DOSPA hydrochloride

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