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Product Information:

CX 614

CX614 is a positive variant modulator of AMPA receptors that enhances excitatory postsynaptic potentials (amplitude and duration) by blocking and slowing the inactivation of responses to glutamate and automatically evokes excitatory postsynaptic currents in neuronal cultures. CX614 can be used in the study of psychiatric disorders such as depression.

Cat. No.: EX-A5529    Purity: >98%
Chemical
Chemical structure of CX 614


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg485In-stock
1g685In-stock
5g1485In-stock
10g2485In-stock


CAS No.191744-13-5
Purity>98%
FormulaC13H13NO4
Mol Weight247.2466
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. Ice bag + foam box available upon request
 
 
Reference:  

[1]. Wei Dai, et al. The Impact and Mechanism of a Novel Allosteric AMPA Receptor Modulator LCX001 on Protection Against Respiratory Depression in Rodents. Front Pharmacol. 2019 Feb 19;10:105.

[2]. Eleni Dicou, et al. Positive allosteric modulators of AMPA receptors are neuroprotective against lesions induced by an NMDA agonist in neonatal mouse brain. Brain Res. 2003 Apr 25;970(1-2):221-5.

CoACoA of CX 614

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