Product Information:
Cat. No.: EX-A2577 | Purity: >98% |
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CAS No. | 1610759-22-2 |
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Purity | >98% |
Formula | C28H30N6O3 |
Mol Weight | 498.5762 |
Appearance | solid powder |
Solubility | Soluble in DMSO |
Shelf Life | >2 years if stored properly |
Storage | Powder -20℃ 2 years; In solvent -20℃ 1 month; |
Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Reference: | [1]. Mason JM, et al. Functional characterization of CFI-402257, a potent and selective Mps1/TTK kinase inhibitor, for the treatment of cancer. Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3127-3132.
[2]. Liu Y, et al. Discovery of Pyrazolo[1,5-a]pyrimidine TTK Inhibitors: CFI-402257 is a Potent, Selective, Bioavailable Anticancer Agent. ACS Med Chem Lett. 2016 May 6;7(7):671-5. |
CoA | CoA of CFI-402257 |
Smiles: | CC1=CC(=CC=C1C(=O)NC1CC1)C1=C2N=C(OC3=CN=CC=C3)C=C(NC[C@H]3C[C@@](C)(O)C3)N2N=C1 |
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