BPK-29

BPK-29 is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein (such RBM45 and SNW1) interactions by covalently modifying C274. BPK-29 impairs the anchorage-independent growth of KEAP1-mutant cancer cells.


Cat. No.: EX-A4714	Purity: >98%

	Chemical structure of BPK-29

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	550	In-stock
100mg	850	In-stock
250mg	1500	In-stock

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CAS No.	2143467-62-1
Purity	>98%
Formula	C26H32ClN3O3
Mol Weight	470.004
Appearance	Solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Bar-Peled L, et al. Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer. Cell. 2017 Oct 19;171(3):696-709.e23.
CoA	CoA of BPK-29

Smiles:	C(N(CC1=CC=CC=C1)C1CCCN(C(=O)C2=CC=C(N3CCOCC3)C=C2)CC1)(=O)CCl


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