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Product Information:

BGB16673

BGB- 16673 is a heterobifunctional small molecule that binds to BTK and E3 ligase, resulting in BTK degradation via ubiquitination.

Cat. No.: EX-A8316    Purity: >98%
Chemical
Chemical structure of BGB16673


For research only, Do not use for Human!

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SynonymsBGB-16673
CAS No.2736508-65-7
Purity>98%
FormulaC47H54N12O4
Mol Weight851.0097
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. First Results from a Phase 1, First-in-Human Study of the Bruton's Tyrosine Kinase (BTK) Degrader Bgb-16673 in Patients (Pts) with Relapsed or Refractory (R/R) B-Cell Malignancies (BGB-16673-101). DOI: 10.1182/blood-2023-180109
CoACoA of BGB16673

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