AUTAC2

AUTAC2 is a FKBP12-targeting autophagy-mediated degrader (AUTAC). AUTAC2 contains an FBnG (p-Fluorobenzyl Guanine) and an SLF (c ligand of FKBP) moiety. SLF binds non-covalently to FKBP12 .


Cat. No.: EX-A11405	Purity: >98%

	Chemical structure of AUTAC2

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
5mg	822	In-stock
10mg	1122	In-stock
25mg	2100	In-stock
50mg	3400	In-stock
100mg	5800	In-stock
250mg	get quote	In-stock

Send PO to E-mail:order@excenen.com; or Fax:+86 020 81619670

Discount Request


CAS No.	2241669-08-7
Purity	>98%
Formula	C61H81FN10O14S
Mol Weight	1229.418
Appearance	white to off-white solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Daiki Takahashi, et al. AUTACs: Cargo-Specific Degraders Using Selective Autophagy. Mol Cell. 2019 Dec 5;76(5):797-810.e10.
CoA	CoA of AUTAC2

Smiles:	O=C([C@@H](NC(C)=O)CSC1=NC2=C(N=C(N)NC2=O)N1CC3=CC=C(F)C=C3)NCCCOCCOCCOCCCNC(CCC(NC4=CC=CC([C@@H](CCC5=CC=C(OC)C(OC)=C5)OC([C@@H]6CCCCN6C(C(C(C)(CC)C)=O)=O)=O)=C4)=O)=O


		Search