ART812

ART812 is an orally active DNA polymerase Polθ inhibitor with an IC50 value of 7.6 nM. ART812 has an IC50 value of 240 nM for cell based microhomology-mediated end joining (MMEJ).


Cat. No.: EX-A8350	Purity: >98%

	Chemical structure of ART812

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	325	In-stock
50mg	585	In-stock
100mg	785	In-stock
250mg	1300	In-stock
500mg	2000	In-stock
1g	2900	In-stock

Send PO to E-mail:order@excenen.com; or Fax:+86 020 81619670

Discount Request


Synonyms	ART-812
CAS No.	2607138-82-7
Purity	>98%
Formula	C19H16ClF4N3O4
Mol Weight	461.795
Appearance	white to off-white solid powder
Solubility	Soluble in DMSO
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Zatreanu D, et al. Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance. Nat Commun. 2021 Jun 17;12(1):3636. [2]. Peter BLENCOWE, et al. Preparation of heterocyclic compounds for use in the treatment of cancer. WO2021028643 A1.
CoA	CoA of ART812


		Search