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Product Information:

AGI-41998

AGI-41998 is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A). AGI-41998 is a brain-penetrant compound. AGI-41998 has the potential for exploring the effects of SAM modulation in the central nervous system (CNS) and research of cancer disease.

Cat. No.: EX-A11788    Purity: >98%
Chemical
Chemical structure of AGI-41998


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg900Inquire
100mg1350Inquire
250mg1950Inquire
1g3800Inquire
2g4900Inquire
5gget quoteInquire


CAS No.2377492-26-5
Purity>98%
FormulaC22H16BrF3N4O2
Mol Weight505.287
Appearancelight yellow to yellow solid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃, 3 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Li M, et al. Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads. J Med Chem. 2022;65(6):4600-4615.

CoACoA of AGI-41998
Smiles:COC1=CC=C(C=C1)N2C=C3C=NC(=NC3=C(C2=O)C4=CC=C(C=C4)Br)NCC(F)(F)F

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