AG-13958

AG-13958 (AG-013958), a potent VEGFR tyrosine kinase inhibitor, is used for treatment of choroidal neovascularization associated with age-related macular degeneration (AMD).


Cat. No.: EX-A11896	Purity: >98%

	Chemical structure of AG-13958

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	700	In-stock
250mg	1200	In-stock
500mg	1800	In-stock
1g	2500	In-stock
5g	get quote	In-stock
10g	get quote	Inquire

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Synonyms	AG-013958
CAS No.	319460-94-1
Purity	>98%
Formula	C26H22FN7O
Mol Weight	467.4976
Appearance	white to off-white solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃, protect from light, 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. M.B. Kosa, et al. Ocular and Systemic Pharmacokinetics of AG-013958 With Sub-Tenon Administration To Cynomologus Monkeys. Investigative Ophthalmology & Visual Science May 2005, Vol.46, 5379. [2]. Solowiej J, et al. Substrate-specific conformational regulation of the receptor tyrosine kinase VEGFR2 catalytic domain. ACS Chem Biol. 2013 May 17;8(5):978-86.
CoA	CoA of AG-13958

Smiles:	CC1=NN(C(=C1)C(=O)NC2=C(C=CC(=C2)NC3=CC4=C(C=C3)C(=NN4)/C=C/C5=CC=CC=N5)F)C


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