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Product Information:

AB928

Etrumadenant (AB928) is an orally bioavailable, selective dual adenosine receptor (A2aR/A2bR) antagonist with immunomodulatory activity.

Cat. No.: EX-A3172    Purity: >98%
Chemical
Chemical structure of AB928


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg660In-stock
1g900In-stock
5g3950In-stock
10g5880In-stock


SynonymsEtrumadenant
CAS No.2239273-34-6
Purity>98%
FormulaC23H22N8O
Mol Weight426.4738
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Seitz L, et al. Safety, tolerability, and pharmacology of AB928, a novel dual adenosine receptor antagonist, in a randomized, phase 1 study in healthy volunteers. Invest New Drugs. 2019 Aug;37(4):711-721.

[2]. Daniel DiRenzo, et al. AB928, a dual antagonist of the A2aR and A2bR adenosine receptors, relieves adenosine-mediated immune suppression [abstract].

CoACoA of AB928
Smiles:N#CC1=CC=CC(C2=NC(N)=NC(C3=CN(CC4=NC(C(C)(O)C)=CC=C4)N=N3)=C2)=C1C

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