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Product Information:

8RK64

8RK64 is a covalent inhibitor of ubiquitin C-terminal hydrolase L1 (UCH-L1; IC50 = 0.32 µM) and a click chemistry reagent.

Cat. No.: EX-A10639    Purity: >98%
Chemical
Chemical structure of 8RK64


For research only, Do not use for Human!

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CAS No.2705841-52-5
Purity>98%
FormulaC14H16N8O2S
Mol Weight360.394
Appearancesolid powder
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Kooij, R., Liu, S., Sapmaz, A., et al. Small-molecule activity-based probe for monitoring ubiquitin C-terminal hydrolase L1 (UCHL1) activity in live cells and zebrafish embryos. J. Am. Chem. Soc. 142(39), 16825-16841 (2020).
CoACoA of 8RK64
Smiles:N#CN1CC[C@@H](C1)C(NC2=NC3=C(S2)CN(CC3)C(CN=[N+]=[N-])=O)=O

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