8-Chloroadenosine

8-Chloroadenosine (8-Cl-Ado), a unique ribonucleoside analog, depletes endogenous ATP that subsequently induces the phosphorylation and activation of AMPK. 8-Chloroadenosine induces autophagic cell death. 8-Chloroadenosine effectively inhibited in vivo tumor growth in mice[1].


Cat. No.: EX-A14437	Purity: >98%

	Chemical structure of 8-Chloroadenosine

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	576	In-stock
250mg	885	In-stock
500mg	1280	In-stock
1g	1895	In-stock
5g	5350	In-stock
10g	8900	In-stock

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Synonyms	8-Cl-Ado
CAS No.	34408-14-5
Purity	>98%
Formula	C10H12ClN5O4
Mol Weight	301.686
Color	White to off-white
State	Solid
Solubility	soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, protect from light; In solvent -20°C, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Christine M Stellrecht, et al. ATP directed agent, 8-chloro-adenosine, induces AMP activated protein kinase activity, leading to autophagic cell death in breast cancer cells. J Hematol Oncol. 2014 Mar 14;7:23.
CoA	CoA of 8-Chloroadenosine

Smiles:	C1=NC(=C2C(=N1)N(C(=N2)Cl)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N


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