7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin)

ZD06519 (7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin)) is a camptothecin analogue and a topoisomerase I inhibitor. ZD06519 is an ADC cytotoxin with a strong bystander effect, inhibiting a variety of malignancies such as HER2-positive and FRα-overexpressing tumors. ZD06519 inhibits DNA cleavage, relaxation, and reconnection processes, inducing tumor cell death. ZD06519 can be used for ADC synthesis and cancer research.


Cat. No.: EX-A11335	Purity: >98%

	Chemical structure of 7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin)

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
1g	get quote	Inquire

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


CAS No.	2873460-17-2
Purity	>98%
Formula	C25H24FN3O7
Mol Weight	497.4724
Color	White to light yellow
State	solid
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, protect from light; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Petersen ME, et al. Design and Evaluation of ZD06519, a Novel Camptothecin Payload for Antibody Drug Conjugates. Mol Cancer Ther. 2024 May 2;23(5):606-618. [2]. Mark Edmund PETERSEN, et al. Camptothecin analogues, conjugates and methods of use. Patent. WO2022246576.
CoA	CoA of 7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin)

Smiles:	CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C5=C(C=C(C(=C5)C)F)N=C4C3=C2)CNC(=O)OCCO)O


		Search