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Product Information:

7-Aminomethyl-10-methyl-11-fluoro camptothecin

7-Aminomethyl-10-methyl-11-fluoro camptothecin is a cytotoxin of MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin . 7-Aminomethyl-10-methyl-11-fluoro camptothecin can be used for the synthesis of camptothecin antibody-drug conjugate (ADC).

Cat. No.: EX-A12604    Purity: >98%
Chemical
Chemical structure of 7-Aminomethyl-10-methyl-11-fluoro camptothecin


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10mg440In-stock
25mg860In-stock
50mg1350In-stock
100mg2200In-stock
250mg4300In-stock
500mg6800In-stock


SynonymsCAMP59
CAS No.2378616-23-8
Purity>98%
FormulaC22H20FN3O4
Mol Weight409.4103
ColorWhite to off-white
Statesolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃, sealed storage, away from moisture and light, 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Li, Wei et al. “Synthesis and Evaluation of Camptothecin Antibody-Drug Conjugates.” ACS medicinal chemistry letters vol. 10,10 1386-1392. 6 Sep. 2019, doi:10.1021/acsmedchemlett.9b00301

[2]. https://ir.cytomx.com/static-files/b4ea6293-b6e1-4b77-80a7-796dd137031c

CoACoA of 7-Aminomethyl-10-methyl-11-fluoro camptothecin
Smiles:O=C1N2C(C=3C(C2)=C(CN)C=4C(N3)=CC(F)=C(C)C4)=CC5=C1COC(=O)[C@@]5(CC)O

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