653-47 hydrochloride

653-47 hydrochloride, a potentiator, significantly potentiates the cAMP-response element binding protein (CREB) inhibitory activity of 666-15. 653-47 hydrochloride is also a very weak CREB inhibitor with IC50 of 26.3 μM.


Cat. No.: EX-A5141	Purity: >98%

	Chemical structure of 653-47 hydrochloride

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	585	In-stock
100mg	785	In-stock
250mg	1150	In-stock
1g	2100	In-stock
5g	4500	Inquire
10g	6800	Inquire

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Synonyms	(653-47 free base, 1224678-75-4)
CAS No.	1224567-46-7
Purity	>98%
Formula	C20H20Cl2N2O3
Mol Weight	407.29
Color	Pale purple to purple
State	solid powder
Solubility	Soluble in DMSO 250 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, sealed storage, away from moisture; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Xie F, et al. Discovery of a Synergistic Inhibitor of cAMP-Response Element Binding Protein (CREB)-Mediated Gene Transcription with 666-15. J Med Chem. 2019;62(24):11423-11429.
CoA	CoA of 653-47 hydrochloride


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