6-alpha-Hydroxy Paclitaxel

6α-Hydroxy paclitaxel is a primary metabolite of Paclitaxel. 6α-Hydroxy paclitaxel retains a time-dependent effect on organic anion–transporting polypeptides 1B1/SLCO1B1 (OATP1B1) with similar inhibition potency to Paclitaxel, whereas it no longer showed time-dependent inhibition of OATP1B3. 6α-Hydroxy paclitaxel can be used for the research of cancer[1].


Cat. No.: EX-A14973	Purity: >98%

	Chemical structure of 6-alpha-Hydroxy Paclitaxel

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
1mg	740	In-stock
2mg	1160	In-stock
3mg	1420	In-stock
5mg	1890	In-stock
10mg	3030	In-stock
25mg	6050	In-stock

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Synonyms	6α-Hydroxy Paclitaxel
CAS No.	153212-75-0
Purity	>98%
Formula	C47H51NO15
Mol Weight	869.9055
Color	White to off-white
State	Solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃, 3 years; In solvent -20℃, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Mori D, et al. Alteration in the Plasma Concentrations of Endogenous Organic Anion-Transporting Polypeptide 1B Biomarkers in Patients with Non-Small Cell Lung Cancer Treated with Paclitaxel. Drug Metab Dispos. 2020 May;48(5):387-394.
CoA	CoA of 6-alpha-Hydroxy Paclitaxel

Smiles:	CC1=C2[C@H](C(=O)[C@]3([C@H]([C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C4=CC=CC=C4)NC(=O)C5=CC=CC=C5)O)O)OC(=O)C6=CC=CC=C6)[C@@]7(CO[C@@H]7[C@H]([C@@H]3O)O)OC(=O)C)C)OC(=O)C


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