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Product Information:

5-HT1A agonist 1

5-HT1A agonist 1 (Compound Ex.37) is a highly selective 5-HT1a receptor agonist (EC50=0.18 nM). 5-HT1A agonist 1 mimicks serotonin binding to the receptor, promotes postsynaptic membrane hyperpolarization, inhibits neuronal hyperexcitability, and reduces the release of anxiety-related neurotransmitters. 5-HT1A agonist 1 is promising for research of neuropsychiatric diseases.

Cat. No.: EX-A13294    Purity: >98%
Chemical
Chemical structure of 5-HT1A agonist 1


For research only, Do not use for Human!

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CAS No.2410053-15-3
Purity>98%
FormulaC22H27N5O2
Mol Weight393.4821
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Sabnis R W. Novel substituted lactams as 5-HT1A agonists for treating neuropsychiatric diseases[J]. ACS Medicinal Chemistry Letters, 2025.

CoACoA of 5-HT1A agonist 1
Smiles:CC1=C2C(CCN(CCN3CCC(C4=NOC5=C4C=CC=C5)CC3)C2=O)=NN1C

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