5-HT1A/2A antagonist 1

D3/5-HT receptor modulator-1 (compound 5i) is a selective dopamine D3 receptor and 5-HT2A receptor antagonist and a partial 5-HT1A receptor agonist. D3/5-HT receptor modulator-1 shows Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for dopamine D3, 5-HT2A, and 5-HT2A receptors. D3/5-HT receptor modulator-1 has a low affinity for dopamine D2 receptors, 5-HT2C receptors, and hERG channels. D3/5-HT receptor modulator-1 has an atypical antipsychotic profile.


Cat. No.: EX-A13713	Purity: >98%

	Chemical structure of 5-HT1A/2A antagonist 1

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	596	in-stock
50mg	862	in-stock
100mg	1450	in-stock
250mg	get quote	check price and availability
500mg	get quote	check price and availability

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CAS No.	898532-85-9
Purity	>98%
Formula	C24H29N3O2
Mol Weight	391.506
Color	White to off-white
State	Solid
Solubility	DMSO : 50 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years; In solvent -20°C, 1 month.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Butini S, et al. Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors: design, synthesis, and effects on behavior. J Med Chem. 2009 Jan 8;52(1):151-69.
CoA	CoA of 5-HT1A/2A antagonist 1

Smiles:	O=C(NCCCCN1CCN(C2=CC=CC(=C2)C)CC1)C=3OC=4C=CC=CC4C3


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