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Product Information:

(5-Cl)-Exatecan

(5-Cl)-Exatecan is a derivative of Exatecan and a DNA topoisomerase inhibitor. (5-Cl)-Exatecan serves as the cytotoxic payload component in antibody-drug conjugates (ADC) targeting ROR1-positive cancers. (5-Cl)-Exatecan is applicable for the research of ROR1-positive cancers.

Cat. No.: EX-A14114    Purity: >95%
Chemical
Chemical structure of (5-Cl)-Exatecan


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10mg768in-stock
25mg1536In-stock
50mg2458In-stock
100mg3920In-stock


CAS No.2813268-66-3
Purity>95%
FormulaC24H22ClN3O4
Mol Weight451.902
SolubilityDMSO : ? 50 mg/mL
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Tian HJ, et al. Antibody drug conjugate, and preparation method therefor and use thereof. WO2022253035A1. 2022-05-23.

CoACoA of (5-Cl)-Exatecan
Smiles:N[C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(Cl)=C(C)C(CC1)=C62

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