5,7-Dichlorokynurenic acid sodium salt

5,7-Dichlorokynurenic acid (sodium) is the sodium form of 5,7-Dichlorokynurenic acid. 5,7-Dichlorokynurenic acid is a selective and competitive antagonist of the glycine site on the NMDA receptor with a KB of 65 nM. 5,7-Dichlorokynurenic acid, a derivative of kynurenic acid, reduces NMDA-induced neuron injury in rat cortical cell cultures[1].


Cat. No.: EX-A15428	Purity: >98%

	Chemical structure of 5,7-Dichlorokynurenic acid sodium salt

For research only, Do not use for Human!

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Synonyms	5,7-DCKA sodium
CAS No.	1184986-70-6
Purity	>98%
Formula	C10H4Cl2NNaO3
Mol Weight	280.039
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. D McNamara, et al. 5,7-Dichlorokynurenic acid, a potent and selective competitive antagonist of the glycine site on NMDA receptors. Neurosci Lett. 1990 Nov 27;120(1):17-20. [2]. McNamara D, et al. 5,7-Dichlorokynurenic acid, a potent and selective competitive antagonist of the glycine site on NMDA receptors. Neurosci Lett. 1990 Nov 27;120(1):17-20.
CoA	CoA of 5,7-Dichlorokynurenic acid sodium salt

Smiles:	C1=C(C=C(C2=C1NC(=CC2=O)C(=O)[O-])Cl)Cl.[Na+]


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