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Product Information:

4A3-SC10

4A3-SC10 is an ionizable cationic lipid (pKa = 6.57) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA. 4A3-SC10 can be used for drug delivery in cancer .

Cat. No.: EX-A16717    Purity: >98%
Chemical
Chemical structure of 4A3-SC10


For research only, Do not use for Human!

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CAS No.1857340-80-7
Purity>98%
FormulaC83H155N3O16S4
Mol Weight1579.389
 
 
Reference:  

[1].Chen Z, et al. Modular Design of Biodegradable Ionizable Lipids for Improved mRNA Delivery and Precise Cancer Metastasis Delineation In Vivo. J Am Chem Soc. 2023 Nov 8;145(44):24302-24314.

CoACoA of 4A3-SC10
Smiles:CCCCCCCCCCSCC(C(OCCOC(CCN(CCCN(CCCN(CCC(OCCOC(C(CSCCCCCCCCCC)C)=O)=O)CCC(OCCOC(C(CSCCCCCCCCCC)C)=O)=O)C)CCC(OCCOC(C(CSCCCCCCCCCC)C)=O)=O)=O)=O)C

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