L-Lysyl-L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-asparaginyl-L-arginyl-L-glutaminyl-L-leucylglycyl-L-valyl-L-alanyl-L-alanine

MK2-IN-5 (Hsp25 kinase inhibitor) acetate is a Mk2 pseudosubstrate (Ki= 8 μM). MK2-IN-5 acetate targets the protein interaction domain in the MAPK pathway. MK2-IN-5 acetate inhibits HSP25 and HSP27 phosphorylation .


Cat. No.: EX-A9115	Purity: >98%

	Chemical structure of L-Lysyl-L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-asparaginyl-L-arginyl-L-glutaminyl-L-leucylglycyl-L-valyl-L-alanyl-L-alanine

For research only, Do not use for Human!

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Synonyms	Hsp25 kinase inhibitor acetate
Synonyms 2	Mk2 pseudosubstrate acetate
CAS No.	474713-20-7
Purity	>98%
Formula	C61H113N21O16
Mol Weight	1396.681
Color	White to off-white
State	Solid
Solubility	Soluble in H2O
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, sealed storage, away from moisture and light, under nitrogen; In solvent -20℃, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Gaestel M, et al. Peptides as signaling inhibitors for mammalian MAP kinase cascades [J]. Current pharmaceutical design, 2009, 15(21): 2471-2480. [2]. Damarla M, et al. Mitogen activated protein kinase activated protein kinase 2 regulates actin polymerization and vascular leak in ventilator associated lung injury [J]. PloS one, 2009, 4(2): e4600. [3]. Lopes L B, et al. Inhibition of HSP27 phosphorylation by a cell-permeant MAPKAP Kinase 2 inhibitor [J]. Biochemical and biophysical research communications, 2009, 382(3): 535-539.
CoA	CoA of L-Lysyl-L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-asparaginyl-L-arginyl-L-glutaminyl-L-leucylglycyl-L-valyl-L-alanyl-L-alanine


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