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Product Information:

3PO

3PO is a PFKFB3 inhibitor. 3PO reduces glycolytic flux and suppresses glucose uptake. 3PO may be useful agents in combination with other drugs that inhibit cancer cell proliferation.

Cat. No.: EX-A5304    Purity: >98%
Chemical
Chemical structure of 3PO


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
1g750In-stock
5g1750In-stock
10g2750In-stock


Synonyms3PO
CAS No.18550-98-6
Purity>98%
FormulaC13H10N2O
Mol Weight210.2313
ColorLight yellow to yellow
Statesolid powder
SolubilitySoluble in DMSO 60 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Clem B, et al. Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth. Mol Cancer Ther. 2008 Jan;7(1):110-20.

[2]. Schoors S, et al. Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis. Cell Metab. 2014 Jan 7;19(1):37-48.
CoACoA of 3PO

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